Many of these side effects can be managed, and some may go away on their own over time. Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects. Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Stop taking the medication and seek immediate medical attention if any of the following occur:. Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication. Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health.
These factors may affect how you should use this medication. Abdominal stomach conditions: Oxycodone and other narcotic medications may make the diagnosis of abdominal conditions more difficult or it may worsen these conditions.
If you have abdominal problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Accidental Use: When oxycodone is used by anyone other than the person for whom it was prescribed, the effects of the medication may be fatal.
Children are especially at risk. Keep this medication out of sight and reach of children. Alcohol and other medications that cause drowsiness: Do not consume alcohol while taking this medication, as this may lead to dangerous side effects. Other medications that cause drowsiness or slow down your breathing e. Constipation: Constipation happens frequently while taking opioid narcotic pain relievers on a regular basis.
Your doctor will discuss the use of stimulant laxatives, stool softeners, and other measures to be used as required. Controlled-release: Controlled-release forms of this medication are designed to work over 12 hours when swallowed whole. If a tablet is broken, cut, crushed, dissolved, or chewed, the entire hour dose will be absorbed rapidly into your body.
This can be very dangerous, causing serious problems such as slowed breathing and overdose, which can be fatal. Dependence and withdrawal: As with other opioid medications narcotics , this medication may become habit-forming if taken for long periods of time.
Misuse of oxycodone is usually not a problem when it is used appropriately for pain relief. Physical dependence, or tolerance a need to take regular doses to prevent physical symptoms has been associated with narcotic analgesics such as oxycodone.
Withdrawal symptoms may be experienced if the dose is significantly reduced or suddenly discontinued. Reducing the dose gradually under medical supervision can help prevent or decrease these withdrawal symptoms when this medication is no longer required for pain control. Withdrawal symptoms e. If you have been taking this medication for a long time and no longer require it for pain control, you should stop the medication gradually as directed by your doctor.
Difficulty breathing: Oxycodone can cause serious breathing problems, particularly for people having an acute asthma attack or for those with chronic obstructive pulmonary disease chronic bronchitis, emphysema or other conditions that affect breathing. If you experience slowed breathing or difficulty breathing, seek immediate medical attention.
If you have lung problems, or are taking other medications that can slow breathing, you are more at risk for experiencing this. If you have asthma or other breathing disorders, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Difficulty swallowing: There have been reports of choking and difficulty swallowing the controlled-release form of oxycodone. If you experience difficulty swallowing or pain after taking controlled-release oxycodone, contact your doctor immediately. Do not drive or perform other potentially hazardous tasks if this medication affects your ability to do these safely.
Head injury: Oxycodone can cause increased pressure inside the head. If you have an acute head injury or any other condition which increases the pressure inside your head, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Kidney function: Kidney disease or reduced kidney function may cause this medication to build up in the body, causing side effects.
If you have severely reduced kidney function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver function: Liver disease or reduced liver function may cause this medication to build up in the body, causing side effects. If you have severely reduced liver function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Medical conditions: If you have abnormal heart rhythms, reduced adrenal function e. Discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
The immediate-release form of oxycodone is available as a generic drug. The extended-release form is only available as the brand-name drug OxyContin. This article helps you understand the differences and similarities between these two drugs and how they work. Read more: All about opioids and addiction ». OxyContin is a brand-name version of the extended-release form of oxycodone. They are different versions of the same drug.
OxyContin and immediate-release oxycodone belong to a drug class called opioids. A class of drugs is a group of medications that work in a similar way and are often used to treat similar conditions. Immediate-release oxycodone and OxyContin both bind to receptors in your brain and spinal cord.
When they do this, they block pain signals and stop pain. Immediate-release oxycodone is used to treat moderate to severe pain, such as from surgery or an injury. OxyContin is usually reserved for longer-lasting pain from the late stages of a long-term disease, usually cancer. Doctors may sometimes add immediate-release oxycodone to treatment with OxyContin during brief moments when the pain becomes severe. Both immediate-release oxycodone and OxyContin are powerful pain relievers.
They both have been shown to be highly effective at treating pain. Oxycodone immediate-release tablets are available as generic drugs. They usually cost less than OxyContin. Your insurance plan may also prefer generic oxycodone over OxyContin. This means they may cover only one of the drugs or only generic forms.
You should call your insurance company to ask if one drug is preferred over the other. You should also call your pharmacy to see if they keep these drugs in stock. Not all pharmacies carry these drugs. The side effects of oxycodone and OxyContin are very similar. This is because they contain the same active ingredient. The most common side effects of these drugs include:. Learn more: Detailed drug information for oxycodone ». An interaction is when a substance changes the way a drug works.
This can be harmful or prevent the drug from working well. Plasma halflife is h half that of morphine and stable plasma levels are reached within 24 h days for morphine. Most of the drug is metabolised in the liver, while the rest is excreted by the kidney along with its metabolites.
The two main metabolites are oxymorphone--which is also a very potent analgesic--and noroxycodone, a weak analgesic. Oxycodone metabolism is more predictable than that of morphine, and therefore titration is easier. Oxycodone has the same mechanism of action as other opioids: binding to a receptor, inhibition of adenylyl-cyclase and hyperpolarisation of neurons, and decreased excitability.
These mechanisms also play a part in the onset of dependence and tolerance. Long-term administration may be associated with less toxicity in comparison with morphine. In the future, both opioids could be used simultaneously at low doses to reduce toxicity.
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